1. extremophiles and spider webs: adventures in genomics
Betsey Dexter Dyer
Mark D. LeBlanc
Wheaton College (Norton, MA)

4. .

6. Iteration of team-taught “DNA” course Percent women enrolled
Percent of A grades [90-100]
earned by women
initial time
57%
(N=14)
71%
(5 of 7)
second time
50%
(N=10)
100%
(3 of 3)
(Fall 2007)
63%
(N=16)
Margolis and Fisher (2002) in “Unlocking the Clubhouse
As a comparison, enrollment in computer science
courses at Wheaton average
about 10-20% women.

8. .

10. research

11. research
teaching

14. You have some creative questions … You like tinkering …
You (like an old-time explorer)
are adventurous … .

18. methods (in silico) (0) wget_bash/wget -r -nv --accept
"*.ptt,*.fna" -P genome_data
"ftp://ftp.ncbi.nih.gov/genomes/Bacteria/"
my $add_org_sql = "INSERT INTO organisms
(genus, species, strain, ncbi_directory)
VALUES (?,?,?,?)";
(2) $motifCounts{$nextMotif }++;
(3) fit4 <- rpart(tempHyper ~ . , data=newpct4mer,
method="class",control=rpart.control)

21. .

22. play

23. .

27. … … … … …

28. .

29. .

30. . . .

31. References
Chargaff, E Essays on Nucleic Acids. Elsevier, New York, NY.
Dyer, B.D., Kahn, M.J., and LeBlanc, M.D. (2007). Classification and Regression Tree (CART)
analyses of genomic signatures reveal sets of tetramers that discriminate
temperature optima of Archaea and Bacteria. Archaea, v2(3).
LeBlanc, M.D. and Dyer, B.D. (2007). Perl for Exploring DNA. Oxford University Press.
Paydarfar, D. and Schwartz, W.J. (2001). Science 6 April 2001:
Vol no. 5514, p. 13.