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Gal3 Links Inflammation and Insulin Resistance
Marie Siwicki, Camilla Engblom, Mikael J. Pittet Cell Metabolism Volume 24, Issue 5, Pages (November 2016) DOI: /j.cmet Copyright © 2016 Elsevier Inc. Terms and Conditions
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Figure 1 Galectin-3 Produced by Inflammatory Cells Perpetuates Obesity-Induced Insulin-Resistance Li et al. (2016) present a model wherein inflammatory cells—likely macrophages—in obese tissue express Gal3, which (1) perpetuates inflammatory cell seeding of the adipose tissue from circulation, and (2) directly inhibits signaling via the insulin receptor. Cell Metabolism , DOI: ( /j.cmet ) Copyright © 2016 Elsevier Inc. Terms and Conditions
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