1. Volume 70, Issue 3, Pages e72-e74 (September 2016)
Re: Daniel M. Geynisman. Anti-programmed Cell Death Protein 1 (PD-1) Antibody Nivolumab Leads to a Dramatic and Rapid Response in Papillary Renal Cell Carcinoma with Sarcomatoid and Rhabdoid Features. Eur Urol 2015;68:912–4 
Francesco Piva, Matteo Santoni, Marina Scarpelli, Alberto Briganti, Antonio Lopez-Beltran, Liang Cheng, Rossana Berardi, Francesco Montorsi, Rodolfo Montironi 
European Urology 
Volume 70, Issue 3, Pages e72-e74 (September 2016)
DOI: /j.eururo
Copyright © 2016 European Association of Urology Terms and Conditions

2. Fig. 1
Connection between PBRM1 mutational status and programmed death ligand 1 (PD-L1) expression. (a) MiR-34a transcription is induced by the p53 transcription factor that, in turn, can be activated by BAF180, encoded by PBMR1. (b) Mutations that impair BAF180 by p53 could downregulate miR-34a, the consequence being that PD-L1 expression in cancer cells would no longer be silenced.
PD-L1=programmed death ligand 1.
European Urology  , e72-e74DOI: ( /j.eururo )
Copyright © 2016 European Association of Urology Terms and Conditions