1. Levetiracetam accumulation in renal failure causing myoclonic encephalopathy with triphasic waves 
Serge Vulliemoz, Patricia Iwanowski, Theodor Landis, Pierre Jallon 
Seizure - European Journal of Epilepsy 
Volume 18, Issue 5, Pages (June 2009)
DOI: /j.seizure
Copyright © 2009 British Epilepsy Association Terms and Conditions

2. Fig. 1
EEG (all panels with Low Pass filter 70Hz, High Pass 0.3Hz, Notch 50Hz, 20s/page): (a) diffuse slowing with multifocal triphasic waves (arrows) associated with levetiracetam accumulation; (b) normalization of the EEG after down titration of levetiracetam according to the renal function; (c) relapse of myoclonic jerks 48h after total cessation of levetiracetam. Epileptogenic focus with spikes and polyspikes at the vertex occurring with/without or without synchronous myoclonic jerks (thick/thin arrow); (d) same EEG page as (c), displayed in a transverse montage to highlight the paramedian localisation of the epileptiform discharges.
Seizure - European Journal of Epilepsy  , DOI: ( /j.seizure )
Copyright © 2009 British Epilepsy Association Terms and Conditions