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Chapter 11 Intro to Genetics
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Question of the day How many hybrids are there on the earth?
All humans, plants, animals, even some cars are hybirds - there is no such thing as “pure bred”
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11-1 Father Gregor Mendel Who was he?
Austrian monk, who taught Biology and grew plants for the monastery. Originally from Czech Republic in 1822 Worked with pea plants
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Genetics Why is what Mendel studied important?
Studied the foundation of genetics (1st time anyone did) Genetics - scientific study of heredity What does heredity mean? Inheirit DNA from prior generations
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What is Geneology? The study of your ancestors and family tree
Often determined by your name Where your ancestors lived Parents occupation or livelihood Ethnic background Etc
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What are genes? Genes are your chromosomes How many do you have?
You have 25, ,000 genes What do they do? Carry info to determine your traits
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What are traits? Traits are the physical features passed down to you from parents, grandparents, etc. What are some good examples? Eye color Hair Color & texture Widows peak Skin Color Bone features (dimples, pronounced chin, etc.)
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Genes & Dominance GM studied specific charac. passed onto generations called traits Parents (P) pass down traits to offspring (F1) Why is it called F1? F1 = 1st filial (latin for son/daughter)
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Parents & Characteristics
All Parents (P) are TRUE- BREEDING (if self fertilized would produce identical F1) Two parents w/ diff. traits produce cross (HYBRID) F1 Pass down GENES (chem factors for traits) Diff. kinds/types of genes are ALLELES Some alleles are DOMINANT over others
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Future Generations Called F2 and so on
When F1 reproduces alleles SEGREGATE or pull apart Then GAMETES form (sex cells for reproduction)
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11-2 Punnett Squares P.S. - The outcome diagram for offspring
Can predict F1, F2… from P cross Takes alleles and crosses them Shows the PROBABILITY of genetic outcomes
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Phenotype & Genotype Organism with same alleles HETEROZYGOUS -
Organism with diff. alleles PHENOTYPE - physical characterist. GENOTYPE - genetic makeup All dominant alleles will show phenotype
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11-3 Exploring Mendel’s Genetics
INDEPENDENT ASSORTMENT - Parent Alleles will separate independently and then recombine in offspring One-Factor Cross - tracking 1 allele Two-Factor Cross - tracking 2 alleles
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Summary of Mendel’s Principles
Individuals inherit genes, passed down from parents If 2 forms of a gene exist, 1 is dominant other is recessive Parents have 2 copies of each gene, only pass 1 to offspring Alleles segregate independently
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Different Types of Dominance/Recession
Some traits are controlled by multiple alleles that aren’t dominant or recessive Incomplete Dominance - where heterozygous phenotype ends up in between two dominant phenotypes
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Codominance Two or more alleles contribute to one combined phenotype
Example Horses Roan Coat - made up of brown & gray hair looks reddish
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Multiple Alleles Genes that have >2 alleles for a trait
Combine to have multiple dominant phenotypes Examples - Rabbit coat colors & blood types
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Polygenic Traits Traits controlled by 2 or more genes
“Having many genes” Example - Human skin color is controlled by 4 different genes Lots of variations
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11-4 Meiosis Just like Mitosis only with 2 rounds of it
Have HOMOLOGOUS pairs - 2 sets of chromosomes (1 from each parent) Homologous pairs are DIPLOID - 2 sets of chromosomes Some reproducing organisms are HAPLOID 1 set of chromsomes
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Phases of Meiosis A form of gamete (sex cells, not regular cells)
Two cycles of mitosis Called MEIOSIS I & II Cuts all Diploid chromosomes in 1/2 End up with 4 daughter cells
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Meiosis I Interphase& Prophase I - Pairs of chromosomes come together form TETRAD Sometimes in tetrad, chromosomes get tangled up (CROSS-OVER) & exchange genetic info Metaphase - Chromosomes lineup Anaphase - Get separated by spindles & pull homologous cells away Telophase&Cytokinesis - cytoplasm, nuclear mem. (2 daughter cells)
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Meiosis I Picture
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Meiosis II From Meiosis I have 2 haploid daughter cells (Prophase II)
Metaphase II- Chromosomes lineup and separate on spindles (like mitosis) Anaphase II - Chromatids get pulled apart Telophase II & Cytokinesis - nuclear mem. & cytoplasm End up with 4 daughter cells
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Gamete Formation Males make 4 sperm cells
Females make 1 egg & 3 polar bodies Only cells in human body that undergo meiosis
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Differences Between Meiosis & Mitosis
4 Daughter Cells Gametes (Sex Cells) 2 Cycles of Mitosis Only 1/2 time Interphase Diploid & Haploid Chromosomes Tetrads Mitosis 2 Daughter Cells All cells except Gametes 1 Cycle only Interphase each time Diploid Only No Tetrads
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11-5 Gene Linkage All alleles occur are on same gene in every human
Some come together and are”linked” These genes can be tracked or mapped Gene Map - locations of certain alleles on genes
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