1. Effect of Peptide YY3–36 on Food Intake in Humans
Lukas Degen, Sibylle Oesch, Michel Casanova, Stefanie Graf, Silvia Ketterer, Juergen Drewe, Christoph Beglinger 
Gastroenterology 
Volume 129, Issue 5, Pages (November 2005)
DOI: /j.gastro
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2. Figure 1
Daily time course of procedures for studies with exogenous PYY3–36.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

3. Figure 2
Plasma PYY concentrations after ingestion of a light lunch (500 kcal) or a large lunch (1500 kcal) in 12 healthy subjects. The large lunch (1500 kcal) induced a significantly higher PYY response than the light lunch (P < .05). Data are expressed as mean ± SEM.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

4. Figure 3
Area under the curve over 120 minutes of PYY measured in plasma (pg/mL) in response to 2 different meals or to graded doses of intravenous PYY3–36 or placebo. The PYY responses expressed as area under the curve over 120 minutes were significantly higher after exogenous infusion compared with meal ingestion (P < .05–.001). Data are expressed as mean ± SEM.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

5. Figure 4
Subjective sensations of hunger experienced by healthy male subjects before and after food intake during intravenous infusion of saline (control) or 1 dose (0.2, 0.4, or 0.8 pmol·kg−1·min−1) of human PYY3–36. Results are expressed as mean ± SEM. n = 16. No statistical differences were observed for hunger and fullness scores with the 2 lower doses of treatment. The highest dose of PYY significantly reduced hunger feelings in the premeal period (P < .05).
Gastroenterology  , DOI: ( /j.gastro )
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6. Figure 5
Plasma PYY concentrations (pg/mL) in response to graded doses of intravenous PYY3–36 or placebo. Plasma PYY concentrations were significantly increased with each dose of PYY compared with placebo (P < .01–.001). Data are expressed as mean ± SEM.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

7. Figure 6
Correlation (r = 0.999; P < .001) between graded doses of exogenous human PYY3–36 and plasma PYY concentrations (expressed as area under the curve). Data are expressed as mean ± SEM.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

8. Figure 7
Ghrelin concentrations measured in plasma (ng/mL) in response to intravenous PYY3–36 (0.8 pmol·kg−1·min−1) or placebo before and after meal intake. In the premeal period, PYY3–36 (0.8 pmol·kg−1·min−1) induced a significant reduction in plasma ghrelin concentrations (P < .05 at time point 0, PYY vs placebo). Data are expressed as mean ± SEM.
Gastroenterology  , DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions