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Vascularized Composite Allotransplant in the Realm of Regenerative Plastic Surgery  Harvey Chim, MD, Hatem Amer, MD, Samir Mardini, MD, Steven L. Moran,

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1 Vascularized Composite Allotransplant in the Realm of Regenerative Plastic Surgery 
Harvey Chim, MD, Hatem Amer, MD, Samir Mardini, MD, Steven L. Moran, MD  Mayo Clinic Proceedings  Volume 89, Issue 7, Pages (July 2014) DOI: /j.mayocp Copyright © 2014 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Figure 1 One-year first cadaveric renal allograft survival and rejection episodes over time. The figure illustrates the best reported 1-year cadaveric renal allograft survival and incidence of rejection over a 45-year period. The time that various immunosuppressive medications were introduced is indicated by their position on the graph. AZA = azathioprine; CY-A = cyclosporine A; FTY720 = fingolimod; 6-MP = 6-mercaptopurine; MMF = mycophenolate mofetil. From Semin Dial,8 with permission. Mayo Clinic Proceedings  , DOI: ( /j.mayocp ) Copyright © 2014 Mayo Foundation for Medical Education and Research Terms and Conditions

3 Figure 2 A 29-year-old man sustained a self-inflicted gunshot wound to the face several years ago. He had undergone mandible reconstruction as well maxilla reconstruction with vascularized fibula and iliac flaps. His nose was reconstructed with a prosthesis. A, New nasal prosthesis with excellent color match to native skin. B, Several months after wearing the prosthesis in the sun. Mayo Clinic Proceedings  , DOI: ( /j.mayocp ) Copyright © 2014 Mayo Foundation for Medical Education and Research Terms and Conditions

4 Figure 3 Patient with a severe facial deformity caused by a blast injury. A, Reconstruction with a latissimus dorsi myocutaneous flap. B, After several debulking procedures, there was adequate space in the orbits and around the cheek and mouth to fit a prosthesis. C, Osteointegrated implants were placed to provide an anchor for a prosthesis. D, Face prosthesis. E, The face prosthesis in place looks good in repose. F, With animation, the prosthesis has an unnatural appearance. Mayo Clinic Proceedings  , DOI: ( /j.mayocp ) Copyright © 2014 Mayo Foundation for Medical Education and Research Terms and Conditions


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