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Published byΝικομήδης Μεταξάς Modified over 6 years ago
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Bioavailability and Cardiovascular Effects of Adrenaline Administered by Anapen Autoinjector in Healthy Volunteers Thierry Duvauchelle, MD, Philippe Robert, PhD, Yves Donazzolo, MD, Sabrina Loyau, PharmD, Bernard Orlandini, MSc, Philippe Lehert, PhD, Jeanne-Marie Lecomte, PhD, Jean-Charles Schwartz, PhD The Journal of Allergy and Clinical Immunology: In Practice Volume 6, Issue 4, Pages (July 2018) DOI: /j.jaip Copyright © 2017 The Authors Terms and Conditions
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Figure 1 Ultrasonographic images of the skin of a normal weight male subject before (left) and after (right) injection of 0.3 mg adrenaline using the Anapen autoinjector. The dotted lines and letter A denote the skin limit (left) or the bolus localization (right). The Journal of Allergy and Clinical Immunology: In Practice 2018 6, DOI: ( /j.jaip ) Copyright © 2017 The Authors Terms and Conditions
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Figure 2 Ultrasonographic images of the skin of an overweight female subject before (left) and after (right) injection of 0.3 mg adrenaline using the Anapen autoinjector. The dotted line and letter A denote the skin limit (left) or the bolus localization (right). The Journal of Allergy and Clinical Immunology: In Practice 2018 6, DOI: ( /j.jaip ) Copyright © 2017 The Authors Terms and Conditions
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Figure 3 Changes in adrenaline plasma levels and HR according to various conditions. The Journal of Allergy and Clinical Immunology: In Practice 2018 6, DOI: ( /j.jaip ) Copyright © 2017 The Authors Terms and Conditions
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