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Immediate-type hypersensitivity reaction to ingestion of mycoprotein (Quorn) in a patient allergic to molds caused by acidic ribosomal protein P2  Michael.

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Presentation on theme: "Immediate-type hypersensitivity reaction to ingestion of mycoprotein (Quorn) in a patient allergic to molds caused by acidic ribosomal protein P2  Michael."— Presentation transcript:

1 Immediate-type hypersensitivity reaction to ingestion of mycoprotein (Quorn) in a patient allergic to molds caused by acidic ribosomal protein P2  Michael Hoff, MSca, Ralph M. Trüeb, MDb, Barbara K. Ballmer-Weber, MDb, Stefan Vieths, PhDa, Brunello Wuethrich, MDb  Journal of Allergy and Clinical Immunology  Volume 111, Issue 5, Pages (May 2003) DOI: /mai Copyright © 2003 Mosby, Inc. Terms and Conditions

2 Fig. 1 EAST inhibition. A, Patient's serum was preincubated for 1 hour with increasing amounts of either Quorn extract or rFus c 1. After subsequent incubation with mycoprotein immobilized on paper disks, residual IgE-binding capacity was measured. B, Same experiment as before using rFus c 1 immobilized on paper disks. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2003 Mosby, Inc. Terms and Conditions

3 Fig. 2 Blot inhibition. For each blot strip, serum from the Quorn-sensitized patient was preincubated with either protein of the in-house extracts as indicated or rFus c 1. Detection of the bound IgE antibodies was performed with an alkaline phospatase-conjugated mouse anti-human IgE antibody and NBT/BCIP as substrate. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2003 Mosby, Inc. Terms and Conditions

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