1. 11 December 2009 Renal Physiology
Test Folder Reviews 6-8 pm Sunday & Monday,
In Botany Lab
Abstracts: Turn in when finished or no later than 9:00 am Wednesday
Course Evaluations
On-line

2. Review of water permeability in various segments
Fig a
14.02a.jpg

3. Figure 14.17 To be emphasized during Urinalysis Lab.
Countercurrent Multiplier & Countercurrent Exchange

4. Effect of Aldosterone: insertion of more Na+K+ATPase into basolateral membrane
Effect: Increase Na+ reab and Increase K+ Secretion

5. Figure 14.30
Apply this information to each of the three Test Beverages used in the Urinalysis Lab!
Cell in the adrenal cortex that respond to AII are also receptors for plasma K+ concentration.
Sodium reabsorption and potassium secretion are coupled.

6. Effect of ADH: insertion of more aquaporins in th the membranes
Effect: Increase H2O reabsorption

7. Apply this information to each of the three Test Beverages used in the Urinalysis Lab!

8. Lung-kidney connection
Acid-Base Balance

9. Figure 14.31
Normally, all filtered bicarbonate is “reabsorbed”

10. Figure 14.32 This process is increased during metabolic acidosis
Excess H+ eliminated in urine bound to phosphate buffer.

11. Figure 14.33 This process is increased during metabolic acidosis
Filtration
Reabsorption
Secretion
Metabolism
Metabolism of glutamine in tubular cells generate bicarbonate buffer.
This process is increased during metabolic acidosis

12. Father-in-law with emphysema (respiratory case studies lab)
PaCO2 =30 mmHg, plasma pH = 7.47
Hyperventilating: ventilation in excess of metabolism to compensate for loss of alveolar surface area for diffusion of O2
Commensurate loss of CO2
RESPIRATORY ALKALOSIS
Renal compensation……… retain H+ and eliminate HCO3-
Review 3 previous slides.

13. Table 14.08 For exam: understand the ventilatory compensation for
Metabolic acidosis as a result of diarrhea and
Metabolic alkalosis as a result of vomiting.

14. Table 14.07

15. Table 14.06