1. Basic Pharmacology http://www. slideworld. org/slideshow
Carl B. Goodman, Ph.D.
Professor Pharmacology
College of Pharmacy & Pharmaceutical Sciences
Florida A&M University
308E FSH-SRC

2. Pharmacology Pharmacology – Toxicology – Study of drug action
Pharmacodynamics:
Pharmacokinetics:
Toxicology –
Mechanism of drug action the effect of the drug at the receptor site
Examines drug absorption, distribution, metabolism & excretion of drugs
Study of harmful effects or side effects of compounds on organisms

3. History of Pharmacology
Paracelsus ( AD) Swiss Scholar & Alchemist “Founder of Pharmacology”
It is the task of chemistry to produce medicines for the treatment of disease since the vital functions are basically chemical in nature. All things are poisons, fro there is nothing without poisonous qualities. It is only the dose, which makes things poison.”

4. History of Pharmacology
Chemical Drug Development
1805 isolation of Morphine, the first chemically pure drug
1860 synthesis of Salicylic acid
1899 synthesis of Acetyl salicylic acid
1935 synthesis of Sulfonamide
1960 design of first B1-blockers

5. Drug Names
FDA
Brand Names (Advil ®)
IUPAC
Generic Names (Ibuprofen)

6. Pharmacology What is a drug? What is pharmacology? Pharmacokinetics
Any chemical agent which effects any biological process
What is pharmacology?
The study of how drugs effect biological systems
Pharmacokinetics
What the body does to the drug
Pharmacodynamics
What the drug does to the body
Pharmacotherapeutics
The study of the use of drugs

7. Physical Nature of Drugs
Solid, Liquid and Gas
Routes of Administration
Inorganic Drugs
Organic Drugs

8. Drug Size
Lithium
Thrombolytic Enzyme

9. Drug – Receptor Complex
Drug Size
Drug Shape: Carvedilol-beta blocker
Receptor
Chemical Bonds
Covalent
Electrostatic
Hydrophobic