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Autologous in vitro reconstituted epidermis in the treatment of a large nevus depigmentosus  Desanka Raskovic, MD, Sergio Bondanza, BSc, Tommaso Gobello,

Published byΜήδεια Δοξαράς Modified over 6 years ago

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Presentation on theme: "Autologous in vitro reconstituted epidermis in the treatment of a large nevus depigmentosus  Desanka Raskovic, MD, Sergio Bondanza, BSc, Tommaso Gobello,"— Presentation transcript:

1 Autologous in vitro reconstituted epidermis in the treatment of a large nevus depigmentosus 
Desanka Raskovic, MD, Sergio Bondanza, BSc, Tommaso Gobello, MD, Antonio Luci, MD, Giovanna Zambruno, MD, Rudolf Happle, MD, Liliana Guerra, MD  Journal of the American Academy of Dermatology  Volume 54, Issue 5, Pages S238-S240 (May 2006) DOI: /j.jaad Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 A, Large nevus depigmentosus showing segmental arrangement on right side of abdomen. Normally pigmented and hyperpigmented macules are present within hypopigmented area. B, Transmission electron microscopic examination of depigmented skin: melanocyte (m) containing very few melanosomes (∗) is visible above basal lamina. Amount of melanosomes is likewise markedly reduced in neighboring keratinocyte (k). C, Six months after grafting, almost complete repigmentation was detected. D, Transmission electron microscopic examination of treated skin area 16 months after grafting: m with several melanosomes (∗) is visible above basal lamina. Many melanosomes in various stages of melanization are visible in surrounding k. (Original magnification ×3900.) Journal of the American Academy of Dermatology  , S238-S240DOI: ( /j.jaad ) Copyright © 2006 American Academy of Dermatology, Inc. Terms and Conditions

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