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Published byTove Samuelsen Modified over 6 years ago
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T2DM, CV Safety, and Efficacy: DPP-4 Inhibitors in focus
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DPP-4 Inhibitor CV Outcomes Trials in T2DM
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T2DM CV Outcomes Trials From the DPP-4 Inhibitor Class
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SAVOR-TIMI 53: Primary Endpoint
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SAVOR-TIMI 53: Hospitalization for HF
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EXAMINE: Primary Endpoint
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EXAMINE: Hospitalization for HF
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TECOS: Study Design
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TECOS: Effect of Sitagliptin vs Placebo on CV Outcomes in T2DM
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TECOS: Hospitalization for HF
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DPP-4 Inhibitors: Hypoglycemia
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DPP-4 Inhibitors: Pancreatitis
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Future DPP-4 CV Outcomes Trials in T2DM
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Managing T2DM: incorporating injectable fixed-dose combinations
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Fixed-dose Combinations
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Why Combine Basal Insulin and GLP-1 RAs?
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DUAL-I: HbA1c Comparison
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DUAL-I: Percentage of Patients to Target HbA1c
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DUAL-I: Change in Body Weight
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DUAL-I: Confirmed Hypoglycemia
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DUAL-I: Nausea Over 26 Weeks
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Addition of Insulin to GLP-1 RA and Addition of GLP-1 RA to Insulin in T2DM
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When and How Should We Use Combination Therapies?
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T2DM, CV SAFETy, and efficacy: GLP-1 Receptor Agonists in focus
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ELIXA: Severe Symptomatic Hypoglycemia
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T2DM, CV SAFETy, and efficacy: SGLT2 Inhibitors in focus
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EMPA-REG OUTCOME
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EMPA-REG OUTCOME: Study Design
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EMPA-REG OUTCOME: Effect of Empagliflozin vs Placebo on the Primary Composite Outcome
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EMPA-REG OUTCOME: Effect of Empagliflozin vs Placebo on CV Death
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EMPA-REG OUTCOME: Effect of Empagliflozin vs Placebo on Individual CV Endpoints
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EMPA-REG OUTCOME: Effect of Empagliflozin vs Placebo on All-cause Mortality
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EMPA-REG OUTCOME: Effect of Empagliflozin vs Placebo on HF Hospitalization
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Future SGLT2 Inhibitor CV Outcomes Trials
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