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Investigation of Colonic and Whole-Gut Transit With Wireless Motility Capsule and Radiopaque Markers in Constipation  Satish S.C. Rao, Braden Kuo, Richard.

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Presentation on theme: "Investigation of Colonic and Whole-Gut Transit With Wireless Motility Capsule and Radiopaque Markers in Constipation  Satish S.C. Rao, Braden Kuo, Richard."— Presentation transcript:

1 Investigation of Colonic and Whole-Gut Transit With Wireless Motility Capsule and Radiopaque Markers in Constipation  Satish S.C. Rao, Braden Kuo, Richard W. McCallum, William D. Chey, John K. DiBaise, William L. Hasler, Kenneth L. Koch, Jeffrey M. Lackner, Carrie Miller, Richard Saad, Jack R. Semler, Michael D. Sitrin, Gregory E. Wilding, Henry P. Parkman  Clinical Gastroenterology and Hepatology  Volume 7, Issue 5, Pages (May 2009) DOI: /j.cgh Copyright © 2009 AGA Institute Terms and Conditions

2 Figure 1 This shows examples of the SmartPill and ROMs recording in a (A) healthy and (B) constipated subject. The healthy subject shows normal GET at 2.5 hours, normal SBTT at 5.3 hours, and normal CTT at 15.5 hours, and 4 ROMs on the day 2 radiograph. The constipated subject shows a delayed GET at 5.8 hours, normal SBTT at 4.3 hours, and delayed CTT at hours. The day 2 radiograph shows the SmartPill and 24 ROMs and the day 5 radiograph shows that the SmartPill has been expelled but 10 ROMs remain. Clinical Gastroenterology and Hepatology 2009 7, DOI: ( /j.cgh ) Copyright © 2009 AGA Institute Terms and Conditions

3 Figure 2 Box-and-whisker plots for SmartPill CTT in healthy and constipated subjects, and effects of sex. CTT was significantly slower in constipated women and men compared with controls. Clinical Gastroenterology and Hepatology 2009 7, DOI: ( /j.cgh ) Copyright © 2009 AGA Institute Terms and Conditions

4 Figure 3 Box-and-whisker plots for (A) GET, (B) SBTT, and (C) WGTT. GET and WGTT were slower in constipated subjects. Clinical Gastroenterology and Hepatology 2009 7, DOI: ( /j.cgh ) Copyright © 2009 AGA Institute Terms and Conditions


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