1. Title: Anat & Phys 5/1/07 Objectives: Class Topics
1/2/2019
Title: Anat & Phys 5/1/07
Objectives:
To learn about glycolysis and carbohydrate metabolism.
Class Topics
Metabolism
Glycolysis
Krebs cycle
Electron Transport Chain
"Better keep yourself clean and bright. You are the window through which you must see the world."
George Bernard Shaw
Wednesday, January 02, :53 PM

2. Class Assignments Glycolysis quiz 5/3/07 Due this class period
1/2/2019
Class Assignments
What
By When
Glycolysis quiz 5/3/07
Due this class period
Due next class period
Due in the future

3. 1/2/2019
Glycolysis
Animation
Smith College

4. Glycolysis Where? When? Why? Catabolic Anabolic
1/2/2019
Glycolysis
Where?
When?
Why?
Catabolic
Anabolic
What happens to pyruvate

5. Pyruvate Aerobic - presence of oxygen Anaerobic - no oxygen
1/2/2019
Pyruvate
Aerobic - presence of oxygen
enters the Krebs cycle (mitochondrion)
tricarboxylic acid (TCA) cycle
Anaerobic - no oxygen
fermentation pathway
pyruvate forms lactic acid
Lactic acid is transported to liver to be converted

6. Krebs Cycle Pyruvate to Acetyl CoA (Coenzyme A)
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Krebs Cycle
Pyruvate to Acetyl CoA (Coenzyme A)
NADH produced
CO2 produced
Acetyl CoA joins with Oxaloacetate to form Citrate
CoA recycled
Citrate is changed to Isocitrate

7. Krebs Cycle Isocitrate is changed to -ketoglutarate CO2 is released
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Krebs Cycle
Isocitrate is changed to -ketoglutarate
NADH is formed
CO2 is released
-ketoglutarate is changed into Succinyl CoA
ATP is formed

8. Krebs Cycle Succinyl CoA is changed into Succinate
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Krebs Cycle
Succinyl CoA is changed into Succinate
GDP (Guanosine diphosphate) is phosphorylated into GTP which in turn phosphorlates ADP into ATP
Succinate is changed into fumarate
FADH2 is formed
Flavin adenine dinucleotide

9. Krebs Cycle Fumarate is changed into maleate
1/2/2019
Krebs Cycle
Fumarate is changed into maleate
Maleate is changed into Oxaloacetate
NADH is formed