1. Peripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: A case-control study and meta-analysis 
Nader Khandanpour, MD, Gavin Willis, PhD, Felicity J. Meyer, FRCS, Matthew P. Armon, FRCS, Yoon K. Loke, MD, Anthony J.A. Wright, Paul M. Finglas, BSc, Barbara A. Jennings, PhD 
Journal of Vascular Surgery 
Volume 49, Issue 3, Pages (March 2009)
DOI: /j.jvs
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2. Fig 1 A flow diagram of the study selection process.
Journal of Vascular Surgery  , DOI: ( /j.jvs )
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3. Fig. 2
(A) Meta-analysis of MTHFR C677T allele frequency in patients with PAD. Odds ratios for PAD in individuals carrying the MTHFR C677T allele compared with those who were homozygous for the wile type allele. Pooled odds ratio = 1.08 (95% CI 0.98, 1.19); Z (test odds ratio differs from 1) = 1.51, P = .13; I2 (inconsistency) = 45%. (B) Meta-analysis of MTHFR C677T homozygous genotype frequency in patients with PAD. Odds rations for PAD in individuals who were homozygous for the MTHFR C677T allele compared with those who were homozygous for the wild type allele (CC vs TT). Pooled odds ratio = 1.36 (95% CI 1.10, 1.68); Z (test odds ratio differs from 1) = 2.79, P = .0052; I2 (inconsistency) = 7.6%.
Journal of Vascular Surgery  , DOI: ( /j.jvs )
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