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When man turns to stone: Extraosseous calcification in uremic patients
Jürgen Floege Kidney International Volume 65, Issue 6, Pages (June 2004) DOI: /j x Copyright © 2004 International Society of Nephrology Terms and Conditions
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Figure 1 Photograph of right thumb of Patient 1 (A). At first glance, the tumorous calcification resembles a small abscess. (B) Radiograph demonstrates the typical cloudy appearance of the extraosseous calcification (arrowheads) with interwoven fibrous tissue. Kidney International , DOI: ( /j x) Copyright © 2004 International Society of Nephrology Terms and Conditions
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Figure 2 Bone scintigraphic image of Patient 1 following the injection of 570MBq 99mTc-HDP. Note extensive calcification of the lungs (arrows), right thumb (arrow), upper sternum, thyroid region, and base of the skull. Kidney International , DOI: ( /j x) Copyright © 2004 International Society of Nephrology Terms and Conditions
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Figure 3A Chest CT image of Patient 1. Note the large pericardial calcifications (arrows) as well as calcification of the descending aorta (arrowhead). Kidney International , DOI: ( /j x) Copyright © 2004 International Society of Nephrology Terms and Conditions
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Figure 3B Cranial CT image of Patient 1 demonstrating massive vascular calcification of the medial and anterior cerebral arteries. Kidney International , DOI: ( /j x) Copyright © 2004 International Society of Nephrology Terms and Conditions
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Figure 4 Conjunctival calcifications in Patient 1.
Kidney International , DOI: ( /j x) Copyright © 2004 International Society of Nephrology Terms and Conditions
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Figure 5A Teutschländer disease. Massive tumor-like calcification in the region of the left shoulder of a 50-year-old patient on chronic HD who refused phosphate binders. Kidney International , DOI: ( /j x) Copyright © 2004 International Society of Nephrology Terms and Conditions
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Figure 5B,C Intraoperative aspect, showing large nodules of whitish material (B). Histologic examination disclosed 2 calcified areas (C) of different morphology separated by a fibrous septum (F). Whereas the left calcified area shows larger crystals and more cellular reaction, including osteoclast-like cells (insert), the right calcified zone evokes relatively little cellular response (PAS stain, magnification ×50; with insert ×200; specimen kindly provided by R. Knüchel-Clarke, Dept. of Pathology, University Hospital Aachen) (C). Kidney International , DOI: ( /j x) Copyright © 2004 International Society of Nephrology Terms and Conditions
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Kidney International 2004 65, 2447-2462DOI: (10. 1111/j. 1523-1755
Kidney International , DOI: ( /j x) Copyright © 2004 International Society of Nephrology Terms and Conditions
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