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Best Practices in the Clinical Management of Motor Symptoms Associated With Huntington Disease.

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Presentation on theme: "Best Practices in the Clinical Management of Motor Symptoms Associated With Huntington Disease."— Presentation transcript:

1 Best Practices in the Clinical Management of Motor Symptoms Associated With Huntington Disease

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3 This program will include a discussion of off-label treatment and investigational agents not approved by the FDA for use in the US

4 Triad of HD Symptoms

5 Natural History of HD

6 Natural History of Clinical HD

7 Diagnosis of HD

8 Assessing Motor Symptoms

9 UHDRS: DCL vs Q80 Diagnosis

10 Range of Motor Symptoms of HD

11 UHDRS Components: Behavior, Cognitive, and Function

12 UHDRS Components: Motor

13 Motor Symptoms Not Captured on UHDRS

14 Factors in the Decision to Treat Overall Motor Manifestations of HD

15 Initiating Treatment of Overall Motor Symptoms in HD

16 Nonpharmacologic Treatment of the Overall Motor Symptoms of HD

17 Pharmacologic Treatment of Motor Symptoms of HD Other Than Chorea

18 Treatment of Chorea Associated With HD

19 Pharmacologic Treatment of Chorea

20 Tetrabenazine

21 Deutetrabenazine

22 Assessing Treatment Efficacy on Motor Outcomes

23 Tetrabenazine and Deutetrabenazine

24 Treatment of Chorea in HD: Decision Making

25 Other Investigational Therapies

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