1. Bone Cells and Tissue

2. Bone Cells Osteoprogenitor cells- stem cells of bone
Osteo = Bone, Geni = beginning.
Spindle shaped
Oval nucleus
Pale cytoplasm
Found in the covering of the bone, and lining of inner cavity of bone.
Osteoprogenitor cells differentiate into osteoblasts.

3. 2. Osteoblasts- make the extracellular matrix .
Blast = sprout
Cells are more columnar
have well developed Golgi bodies
Osteoblasts differentiate into osteocytes.

4. 3. Osteocytes-maintain the matrix.
Cytes = Cell
Note how osteocytes are connected to each other.
They live in small spaces in the matrix called lacunae.

5. Osteoclasts- secrete acid that breaks down mineralized matrix
Multinucleated
Large
After bone is broken down, what cell will invade the area and deposit new bone matrix?
Osteoblast

6. Bone Tissue Compact bone
Found in the shafts of our long bones and on the inner and outer surface of our flat bones.
Provide strength.
Canaliculi- small tubes in the matirx that connect bone cells
Central/Haversion canal- contains blood vessels
Lacuna- Cavity that holds an osteocyte
Lamellae- layers of matrix
Osteon- cylinder shaped unit 1 2 3 4

7. What is the bone matrix made of?
-25% water
-25% collagen fibers (provide strength, resilience)
-50% inorganic salts- calcium and phosphorus
(hard, resistant to crushing)

8. The Structure of Bone Spongy (cancellous) bone.
Found within flat bones and in the ends of long bones.
Stores red bone marrow
How do you think compact and spongy bone got their name?

9. Bone marrow aspiration and biopsy.

10. Cartilage Hyaline cartilage
-found at ends of long bones between joints
-important in bone growth, protects ends of bones
Fibrocartilage
-found between vertebrae
-cushions

11. Dense Regular Connective tissue
Covering of a bone
Allows for attachment of tendons and ligaments

12. Blood
Found throughout the bone
Brings nutrients, removes wastes

13. -Nervous tissue Found in the covering of the bone
Sends and receives messages

14. Together these tissues function in...
Support and Movement (Explain)
Our bones provide support for sitting and standing.
Our bones act as levers for our muscles to pull against.
Protection (Explain)
Our skulls protect our brain.
Our vertebrae protects our spinal cord.
Our ribcage acts as a shield to protect our important thoracic organs (heart and lungs).

15. 3. Storage (What is bone storing?)
Our skeletal tissue stores minerals that can be released as needed- calcium and phosphorous
Adult long bones store yellow marrow, an energy reserve
Hematopoiesis
-formation of blood cells

16. Homework
Complete Bone Cells and Tissue homework
Color Bone Matrix