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Tyrosine Kinase Inhibitors in Clinical Practice: Patient Selection

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Presentation on theme: "Tyrosine Kinase Inhibitors in Clinical Practice: Patient Selection"— Presentation transcript:

1 Tyrosine Kinase Inhibitors in Clinical Practice: Patient Selection
Jean-Jacques Patard  European Urology Supplements  Volume 7, Issue 9, Pages (September 2008) DOI: /j.eursup Copyright © 2008 European Association of Urology Terms and Conditions

2 Fig. 1 Progression-free survival (PFS) by Memorial Sloan-Kettering Cancer Center risk group in patients treated with sunitinib or interferon-α in the first-line setting. European Urology Supplements 2008 7, DOI: ( /j.eursup ) Copyright © 2008 European Association of Urology Terms and Conditions

3 Fig. 2 Progression-free survival (PFS) by Memorial Sloan-Kettering Cancer Center risk group in patients previously treated with cytokines in the sunitinib expanded-access study. European Urology Supplements 2008 7, DOI: ( /j.eursup ) Copyright © 2008 European Association of Urology Terms and Conditions

4 Fig. 3 Progression-free survival (PFS) in sunitinib-treated patients according to the risk factors derived from a multivariate analysis (phase 3 trial comparing sunitinib to interferon-α). European Urology Supplements 2008 7, DOI: ( /j.eursup ) Copyright © 2008 European Association of Urology Terms and Conditions

5 Fig. 4 Progression-free survival (PFS) in subgroups of patients previously treated with cytokines in the expanded-access study. European Urology Supplements 2008 7, DOI: ( /j.eursup ) Copyright © 2008 European Association of Urology Terms and Conditions

6 Fig. 5 Treatment algorithm for metastatic renal cell carcinoma.
IFN-α, interferon-α; IL-2, interleukin 2; mRCC, metastatic renal cell carcinoma; MSKCC, Memorial Sloan-Kettering Cancer Center; mTOR, mammalian target of rapamycin. European Urology Supplements 2008 7, DOI: ( /j.eursup ) Copyright © 2008 European Association of Urology Terms and Conditions


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