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Robert S. Rhodes, M.D., Alan M. Cohen, M.D. 

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Presentation on theme: "Robert S. Rhodes, M.D., Alan M. Cohen, M.D. "— Presentation transcript:

1 Magnetic resonance imaging and spectroscopy in the study of cardiovascular disease 
Robert S. Rhodes, M.D., Alan M. Cohen, M.D.  Journal of Vascular Surgery  Volume 2, Issue 2, Pages (March 1985) DOI: / (85) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

2 Fig. 1 Lumbar aortogram demonstrating (A) 4.0 cm abdominal aortic aneurysm (AA) and (B) right iliac artery aneurysm (RIA) and left iliac artery occlusion (LIO). Journal of Vascular Surgery 1985 2, DOI: ( / (85) ) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

3 Fig. 2 Coronal slice obtained by MRI of patient in Fig. 1 with arterial findings noted. Vena cava (VC), left iliac (LIV), and right iliac vein (RIV) are also noted. Journal of Vascular Surgery 1985 2, DOI: ( / (85) ) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

4 Fig. 3 Sagittal slice obtained by MRI of patient in Fig. 1. Aortic aneurysm and celiac (CA) and superior mesenteric artery (SMA) are readily seen. Journal of Vascular Surgery 1985 2, DOI: ( / (85) ) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

5 Fig. 4 Cross-sectional slices of normal adult abdomen obtained by MRI gated after R wave of cardiac cycle. Vena cava (VC) and aorta (A) are labeled. A, At 1 msec (late diastole) aorta produces signal indicating slow or no flow. B, At 100 msec (end diastole) there is slightly increased aortic signal compared with A. This is because slow blood flow that has not been previously exposed to field has paradoxically enhanced signal caused by increased response to radio excitation. C, At 200 msec (systole) aorta is black, signifying high flow. D, At 500 msec (early diastole) edges of aortic lumen are black with increased signal from central aorta compared with C. Whether heterogeneity of signal represents laminar and/or turbulent flow remains to be determined. Journal of Vascular Surgery 1985 2, DOI: ( / (85) ) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

6 Fig. 5 31P NMR spectrum from an isolated, perfused normal rat kidney. Area under each peak is proportional to tissue content of that compound. Sugar phosphates and AMP are under sugar phosphate peak; Pi represents inorganic phosphate; PDE is a phosphodiester, probably glycerol phosphorylcholine; PCr is phosphocreatinine, normally low in kidneys; γ ATP, β ADP reflects ATP and ADP content; α ATP, α ADP, NAD reflects ATP, ADP, and ADP content; and β ATP solely reflects ATP content. Journal of Vascular Surgery 1985 2, DOI: ( / (85) ) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

7 Fig. 6 Several spectra from isolated, perfused rat kidney. A, Normal kidney. B, After 20 minutes of hypoxia created by substituting N2 for O2. Note decrease in peaks that reflect ATP content. C, After several cycles of hypoxia and reoxygenation. Note restoration of ATP. Journal of Vascular Surgery 1985 2, DOI: ( / (85) ) Copyright © 1985 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions


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