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Immunoglobulin-responsive refractory epilepsy – 3 cases with a similar EEG pattern  Sasha Dionisio, Helen Brown, Cecilie Lander, Caroline Airey, Alexander.

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Presentation on theme: "Immunoglobulin-responsive refractory epilepsy – 3 cases with a similar EEG pattern  Sasha Dionisio, Helen Brown, Cecilie Lander, Caroline Airey, Alexander."— Presentation transcript:

1 Immunoglobulin-responsive refractory epilepsy – 3 cases with a similar EEG pattern 
Sasha Dionisio, Helen Brown, Cecilie Lander, Caroline Airey, Alexander Lehn, Hozefa Nooruddin, Stefan Blum  Seizure - European Journal of Epilepsy  Volume 22, Issue 5, Pages (June 2013) DOI: /j.seizure Copyright © 2013 British Epilepsy Association Terms and Conditions

2 Fig. 1 (a) Case 1 – EEG, day 9 of super-refractory status epilepticus. Bipolar montage of ongoing left hemispheric and bi-frontal polyspike and 2.5–3Hz spike-wave epileptiform discharges. (b) Case 1 – EEG 12h post IVIg – referential average montage showing generalized slowing. (c) Case 1 – EEG post 5 days IVIg. Return of normal trace. Seizure - European Journal of Epilepsy  , DOI: ( /j.seizure ) Copyright © 2013 British Epilepsy Association Terms and Conditions

3 Fig. 2 (a) Case 2 – EEG during focal status epilepticus: Bipolar montage EEG with right hemisphere continuous epileptiform discharges at 2Hz and infrequent left frontal spikes. (b) Case 2 – EEG post treatment with 2 doses of IVIg. Seizure - European Journal of Epilepsy  , DOI: ( /j.seizure ) Copyright © 2013 British Epilepsy Association Terms and Conditions

4 Fig. 3 (a) Case 3 – Interictal EEG. Continuous 2Hz left hemispheric and right frontal epileptiform discharges. (b) Case 3 – EEG 6 months post IVIg treatment. Marked improvement in EEG. Infrequent right hemisphere discharges seen only during prolonged EEG monitoring. Seizure - European Journal of Epilepsy  , DOI: ( /j.seizure ) Copyright © 2013 British Epilepsy Association Terms and Conditions


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