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Association of Polymorphisms in the Angiotensin-Converting Enzyme Gene with Alzheimer Disease in an Israeli Arab Community  Yan Meng, Clinton T. Baldwin,

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Presentation on theme: "Association of Polymorphisms in the Angiotensin-Converting Enzyme Gene with Alzheimer Disease in an Israeli Arab Community  Yan Meng, Clinton T. Baldwin,"— Presentation transcript:

1 Association of Polymorphisms in the Angiotensin-Converting Enzyme Gene with Alzheimer Disease in an Israeli Arab Community  Yan Meng, Clinton T. Baldwin, Abdalla Bowirrat, Kristin Waraska, Rivka Inzelberg, Robert P. Friedland, Lindsay A. Farrer  The American Journal of Human Genetics  Volume 78, Issue 5, Pages (May 2006) DOI: /503687 Copyright © 2006 The American Society of Human Genetics Terms and Conditions

2 Figure 1 LD block structure in the DCP1 region. The upper triangle shows LD calculated using the r2 measure, and the lower triangle shows LD calculated using the D′ measure. The American Journal of Human Genetics  , DOI: ( /503687) Copyright © 2006 The American Society of Human Genetics Terms and Conditions

3 Figure 2 Proposed mechanisms for influence of ACE on development of AD via a pathway leading to increased production of the toxic form of Aβ (Aβ42) or through the action of vascular risk factors (see text for details). The American Journal of Human Genetics  , DOI: ( /503687) Copyright © 2006 The American Society of Human Genetics Terms and Conditions


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