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W. Greg Miller, Graham R.D. Jones  Advances in Chronic Kidney Disease 

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Presentation on theme: "W. Greg Miller, Graham R.D. Jones  Advances in Chronic Kidney Disease "— Presentation transcript:

1 Estimated Glomerular Filtration Rate; Laboratory Implementation and Current Global Status 
W. Greg Miller, Graham R.D. Jones  Advances in Chronic Kidney Disease  Volume 25, Issue 1, Pages 7-13 (January 2018) DOI: /j.ackd Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

2 Figure 1 Mean bias by peer group vs an isotope dilution mass spectrometry (IDMS) reference measurement procedure for College of American Pathologists 2003 Survey specimen C-02, fresh frozen serum, with creatinine 0.90 mg/dL. Error bars indicate 1.96 × SD for distribution of participant results. The error bars that appear missing are smaller than the plot symbol. The numbers on the horizontal axis identify the instrument manufacturer: 1 is Abbott; 2 is Bayer; 3 is Beckman Coulter; 4 is Dade Behring; 5 is Nova; 6 is Olympus; 7 is Roche; 8 is Schiapparelli; 9 is Toshiba; and 0 is Ortho Vitros. Reprinted with permission from reference.14 Advances in Chronic Kidney Disease  , 7-13DOI: ( /j.ackd ) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

3 Figure 2 Bias vs an isotope dilution mass spectrometry (IDMS) reference measurement procedure for measurements of commutable fresh frozen serum samples by medical laboratory creatinine measurement procedures in College of American Pathologists Surveys. The data are plotted from Table 2 in reference.15 Advances in Chronic Kidney Disease  , 7-13DOI: ( /j.ackd ) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

4 Figure 3 Percent of participants in the College of American Pathologists general chemistry proficiency testing surveys reporting eGFR. Data used with permission. eGFR, estimated glomerular filtration rate. Advances in Chronic Kidney Disease  , 7-13DOI: ( /j.ackd ) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

5 Figure 4 Equations used to calculate eGFR from creatinine by participants in the 2017 College of American Pathologists general chemistry proficiency testing survey. Data used with permission. CKD-EPI, Chronic Kidney Disease Epidemiology Collaboration; eGFR, estimated glomerular filtration rate; IDMS, isotope dilution mass spectrometry; MDRD, Modification of Diet in Renal Disease. Advances in Chronic Kidney Disease  , 7-13DOI: ( /j.ackd ) Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions


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