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Comparing histopathology from patients with X-linked recessive ichthyosis and autosomal recessive congenital ichthyosis with transglutaminase 1 mutation:

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Presentation on theme: "Comparing histopathology from patients with X-linked recessive ichthyosis and autosomal recessive congenital ichthyosis with transglutaminase 1 mutation:"— Presentation transcript:

1 Comparing histopathology from patients with X-linked recessive ichthyosis and autosomal recessive congenital ichthyosis with transglutaminase 1 mutation: A report from the National Registry for Ichthyosis and Related Skin Disorders  Catherine S. Yang, MD, Hyemin Pomerantz, MD, Kathleen A. Mannava, MD, Jessica Corwin, MD, Martin A. Weinstock, MD, PhD, Philip Fleckman, MD, John J. DiGiovanna, MD, Leslie Robinson-Bostom, MD  Journal of the American Academy of Dermatology  Volume 74, Issue 5, Pages e2 (May 2016) DOI: /j.jaad Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 A, ARCI biopsy showing focal parakeratosis, thickened granular layer, acanthosis and psoriasiform hyperplasia. Inset of biopsy from another patient with ARCI showing more prominent hypergranulosis. (Hematoxylin and eosin stain, original magnification ×200). B, XLRI biopsy showing slightly atrophic granular layer and no acanthosis. Both biopsies show compact hyperkeratosis and mild dermal infiltrate. (Hematoxylin and eosin stain, original magnification ×200). ARCI, Autosomal recessive congenital ichthyosis; XLRI, X-linked recessive ichthyosis. Journal of the American Academy of Dermatology  , e2DOI: ( /j.jaad ) Copyright © 2015 American Academy of Dermatology, Inc. Terms and Conditions


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