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Efficacy of a weekly cryotherapy regimen to treat Leishmania major cutaneous leishmaniasis  Ibrahim M. Mosleh, PhD, Eid Geith, MD, Lina Natsheh, BSc,

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Presentation on theme: "Efficacy of a weekly cryotherapy regimen to treat Leishmania major cutaneous leishmaniasis  Ibrahim M. Mosleh, PhD, Eid Geith, MD, Lina Natsheh, BSc,"— Presentation transcript:

1 Efficacy of a weekly cryotherapy regimen to treat Leishmania major cutaneous leishmaniasis 
Ibrahim M. Mosleh, PhD, Eid Geith, MD, Lina Natsheh, BSc, Gabrielle Schönian, PhD, Nabil Abotteen, MD, Sa'ad Kharabsheh, MD  Journal of the American Academy of Dermatology  Volume 58, Issue 4, Pages (April 2008) DOI: /j.jaad Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 A, CL lesions at time of diagnosis on arm of 35-year-old patient. B, Improvement of lesions after first cryosession. C, Healed lesion with negligible scarring and improvement of skin color at 1 week after fifth cryosession (5 weeks). Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Percentage of healed lesions from total number of lesions after cryosessions 1 through 7. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

4 Fig 3 Percentage of healed lesions categorized according to their size after cryosessions 1 through 7. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

5 Fig 4 A and B, One treated (white arrow) and one untreated (black arrow) lesion of a control patient 1 week after the first (A) and the second (B) cryosession. C, Untreated lesion (magnified) 1 week after first treatment of the other lesion. D, Treated lesion (magnified) 1 week after second cryosession. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

6 Fig 5 A, CL lesion on backside of knee of a 2-year-old patient at time of diagnosis. B, Complete healing with hyperpigmentation and hypopigmentation. C, Three years after cryotherapy, amelioration of skin color and healing with excellent cosmetic results. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions

7 Fig 6 A, Noticeable hyperpigmented scar on leg of a patient aged 3 years at time of treatment. B, Scarring with depression on face of a patient who was an infant at the time of treatment. The scar is similar to scars of many self-healed lesions. C and D, Lesions of the scars in A and B, respectively. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2008 American Academy of Dermatology, Inc. Terms and Conditions


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