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Whitney A. High, MD, MEng, Reed A

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Presentation on theme: "Whitney A. High, MD, MEng, Reed A"— Presentation transcript:

1 Gadolinium is detectable within the tissue of patients with nephrogenic systemic fibrosis 
Whitney A. High, MD, MEng, Reed A. Ayers, PhD, John Chandler, PhD, Gary Zito, BS, Shawn E. Cowper, MD  Journal of the American Academy of Dermatology  Volume 56, Issue 1, Pages (January 2007) DOI: /j.jaad Copyright © 2007 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Representative EDS spectrum from specimen 2D demonstrating the 7 characteristic peaks indicative of a gadolinium signature emitted from particles within tissue. Journal of the American Academy of Dermatology  , 21-26DOI: ( /j.jaad ) Copyright © 2007 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Aggregated particles of gadolinium associated with a cell body of a probable macrophages located within dermal fibrosis in specimen 2D. Similar gadolinium deposition was noted in the fibrotic areas of specimen 4A and specimen 7A (not illustrated). (Field emission scanning electron microscope; original magnification: ×2000.) Journal of the American Academy of Dermatology  , 21-26DOI: ( /j.jaad ) Copyright © 2007 American Academy of Dermatology, Inc. Terms and Conditions

4 Fig 3 In many specimens, small particles comprised of other metals were identified, such as this iron particle located 100 μm from a smaller deposit of gadolinium within specimen 2D. (Field emission scanning electron microscope; original magnification: ×700.) Journal of the American Academy of Dermatology  , 21-26DOI: ( /j.jaad ) Copyright © 2007 American Academy of Dermatology, Inc. Terms and Conditions


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