1. a) Biological onset (inception), pre-clinical and clinical phases of the natural history of a disease.
a) Biological onset (inception), pre-clinical and clinical phases of the natural history of a disease. Four different preventive strategies are also illustrated. Tx: treatment. b) Target population and goals of these four preventive strategies. Reproduced from
Alvar Agustí, and Bartolomé Celli ERJ Open Res 2017;3:
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