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TERT Promoter Mutations Occur Frequently in Urothelial Papilloma and Papillary Urothelial Neoplasm of Low Malignant Potential  Liang Cheng, Rodolfo Montironi,

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Presentation on theme: "TERT Promoter Mutations Occur Frequently in Urothelial Papilloma and Papillary Urothelial Neoplasm of Low Malignant Potential  Liang Cheng, Rodolfo Montironi,"— Presentation transcript:

1 TERT Promoter Mutations Occur Frequently in Urothelial Papilloma and Papillary Urothelial Neoplasm of Low Malignant Potential  Liang Cheng, Rodolfo Montironi, Antonio Lopez-Beltran  European Urology  Volume 71, Issue 3, Pages (March 2017) DOI: /j.eururo Copyright © 2016 European Association of Urology Terms and Conditions

2 Fig. 1 TERT promoter mutation status in (A) bladder urothelial papilloma and (C) papillary urothelial neoplasm of low malignant potential (PUNLMP). (B)The TERT promoter mutation C228T was detected in a urothelial papilloma, with a dominant mutant melting peak at 65.5°C (red arrow), and a minor wild-type TERT melting peak at 57°C for benign cells (light orange arrow). (D) The TERT promoter mutation C228T was detected in PUNLMP, with a dominant mutant melting peak (red arrow), and a minor wild-type TERT peak for benign cells (light orange arrow). The peak height is proportional to the percentage of cells in the population tested. European Urology  , DOI: ( /j.eururo ) Copyright © 2016 European Association of Urology Terms and Conditions


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