Download presentation
Presentation is loading. Please wait.
Published byNathaniel Warner Modified over 6 years ago
1
Effects of aggressive blood pressure control in normotensive type 2 diabetic patients on albuminuria, retinopathy and strokes Robert W. Schrier, Raymond O. Estacio, Anne Esler, Philip Mehler Kidney International Volume 61, Issue 3, Pages (March 2002) DOI: /j x Copyright © 2002 International Society of Nephrology Terms and Conditions
2
Figure 1 Design and patient follow up rates for the ABCD Trial.
Kidney International , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions
3
Figure 2 Mean systolic(A) and diastolic (B) blood pressures ± standard errors according to intensive (solid line) versus moderate (dashed line) therapy throughout 5 years. T tests at each time interval revealed a significant and persistent blood pressure separation occurred after 6 months between the two interventions, P < Kidney International , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions
4
Figure 3 Mean total cholesterol (normal range 130 to 200 mg/dL) and glycosylated hemoglobin (normal range 4.2 to 7.0%) values ± standard errors over 5-years for the intensive (solid line) versus moderate (dashed line) therapy (A), and nisoldipine (solid line) versus enalapril (dashed line) therapy(B). T tests at each time interval reveal no significant difference between the therapies. Kidney International , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions
5
Figure 4 Mean creatinine clearances ± standard errors according to (A) intensive (solid line) versus moderate (dashed line) blood pressure control and (B) nisoldipine (solid line) versus enalapril (dashed line). Kidney International , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions
6
Figure 5 Mean creatinine clearances ± standard errors according to intensive (solid line) versus moderate (dashed line) therapy for patients with normoalbuminuria (A) and microalbuminuria (B) at baseline. Kidney International , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions
7
Figure 6 Log urinary albumin excretion (UAE) for intensive (solid line) and moderate (dashed line) blood pressure control groups: (A) normoalbuminuria at baseline; (B) microalbuminuria at baseline. *T test performed at various time intervals revealed a P value <0.05. Kidney International , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions
8
Figure 7 Kaplan-Meier curves demonstrating progression from normoalbuminuria to microalbuminuria (A; P = 0.04) and from microalbuminuria to overt albuminuria (B; P = 0.02 )in patients on (solid line) intensive versus (dashed line) moderate therapy. Kidney International , DOI: ( /j x) Copyright © 2002 International Society of Nephrology Terms and Conditions
Similar presentations
© 2024 SlidePlayer.com. Inc.
All rights reserved.