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Ethnic differences in bone and mineral metabolism in healthy people and patients with CKD
Vanda Jorgetti, Luciene M. dos Reis, Susan M. Ott Kidney International Volume 85, Issue 6, Pages (June 2014) DOI: /ki Copyright © 2014 International Society of Nephrology Terms and Conditions
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Figure 1 Bone histomorphometry findings in white and black subjects without known kidney disease. Histomorphometric parameters that assessed turnover, mineralization, and volume (TMV classification), were obtained from studies of white () and black () individuals, women (♀) and men (♂), in two age brackets: 31–40 years old, near the peak bone mass, and 51–60 years old corresponding to postmenopausal women. Turnover was assessed only in women in premenopause and postmenopause from the values of BFR/BS (μm3/μm2/day). The values of OV/BV and BV/TV both expressed as percentages were used to evaluate mineralization and volume, respectively. Bone turnover was not different among women in both ethnic groups and in both the periods analyzed. In general, mineralization was slower in black women and bone volume was higher. The figure was constructed with results from studies by (1) Schnitzler et al.49 (2) Han et al.53 (3) Han et al.54 (4) Parisien et al.52 (5) Parfitt et al.55 and (6) Dos Reis et al.51 BFR/BS, bone formation rate; BV/TV, trabecular bone volume; OV/BV, osteoid volume. Kidney International , DOI: ( /ki ) Copyright © 2014 International Society of Nephrology Terms and Conditions
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