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A 15-Year Analysis of Early and Late Autologous Hematopoietic Stem Cell Transplant in Relapsed, Aggressive, Transformed, and Nontransformed Follicular.

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Presentation on theme: "A 15-Year Analysis of Early and Late Autologous Hematopoietic Stem Cell Transplant in Relapsed, Aggressive, Transformed, and Nontransformed Follicular."— Presentation transcript:

1 A 15-Year Analysis of Early and Late Autologous Hematopoietic Stem Cell Transplant in Relapsed, Aggressive, Transformed, and Nontransformed Follicular Lymphoma  Mitchell Sabloff, Harold L. Atkins, Isabelle Bence-Bruckler, Christopher Bredeson, Dean Fergusson, Paul Genest, Harry Hopkins, Brian Hutton, Sheryl Mcdiarmid, Lothar B. Huebsch  Biology of Blood and Marrow Transplantation  Volume 13, Issue 8, Pages (August 2007) DOI: /j.bbmt Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Survival from ASCT between the FL-NT and the FL-T. A, Overall survival (OS) [FL-NT versus FL-T, P = .33]; B, Progression-free survival (PFS) [FL-NT versus FL-T, P = .007]. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Overall survival (OS) from diagnosis P = .25.
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Comparison between the time to next treatment (TTNT) prior to ASCT and PFS post ASCT: A, After 1 chemotherapy (CT); B, after 2 CT; C, after >2 CT. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

5 Figure 4 Survival from ASCT based on prior number of chemotherapies (CT). A, progression-free survival. B, Overall survival. Neither is statistically significant. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

6 Figure 5 Overall survival from relapse post-ASCT of those who relapsed postASCT. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

7 Figure 6 Overall survival comparing dose of TBI (1200 cGy in 6 fractions versus 500 cGy in 1 fraction). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2007 American Society for Blood and Marrow Transplantation Terms and Conditions

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