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Matched Related and Unrelated Donor Hematopoietic Stem Cell Transplantation for DOCK8 Deficiency
Jennifer Cuellar-Rodriguez, Alexandra F. Freeman, Jennifer Grossman, Helen Su, Mark Parta, Heardley Murdock, Nirali Shah, Catherine Bollard, Heidi H. Kong, Niki Moutsopoulos, Kelly Stone, Juan Gea-Banacloche, Steven M. Holland, Dennis D. Hickstein Biology of Blood and Marrow Transplantation Volume 21, Issue 6, Pages (June 2015) DOI: /j.bbmt Copyright © Terms and Conditions
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Figure 1 Correction of the oral manifestations of DOCK8 deficiency. (A) Refractory HSV gingivitis and (B) periodontitis in Patient 1. (C and D) Post-transplant day +100 in the same patient. Biology of Blood and Marrow Transplantation , DOI: ( /j.bbmt ) Copyright © Terms and Conditions
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Figure 2 Cutaneous lesions in DOCK8 patients. (A) Severe persistent eczematous dermatitis on dorsal feet of Patient 1 before and after HSCT. (B) Extensive bulky, confluent verrucae on the antecubital fossa and knees of Patient 4 before and after HSCT. (C) Chronic wounds on hands and legs of Patient 2 before and after HSCT. Biology of Blood and Marrow Transplantation , DOI: ( /j.bbmt ) Copyright © Terms and Conditions
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Figure 3 Positron emissions tomography scan of EBV-positive lymphoma in Patient 6, (A) pretransplant, (B) 100 days post-transplant, and (C) 1 year post-transplant. Biology of Blood and Marrow Transplantation , DOI: ( /j.bbmt ) Copyright © Terms and Conditions
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Figure 4 Reconstitution of cellular compartments after HSCT. Leukocyte subsets are shown pretransplant and at 1 year post-transplant. Biology of Blood and Marrow Transplantation , DOI: ( /j.bbmt ) Copyright © Terms and Conditions
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