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Should I Stay or Should I Go: Neuromodulators of Behavioral States

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Presentation on theme: "Should I Stay or Should I Go: Neuromodulators of Behavioral States"— Presentation transcript:

1 Should I Stay or Should I Go: Neuromodulators of Behavioral States
Alexander F. Schier  Cell  Volume 154, Issue 5, Pages (August 2013) DOI: /j.cell Copyright © 2013 Elsevier Inc. Terms and Conditions

2 Figure 1 Serotonin and PDF Signaling Generate Behavioral States in C. elegans (A) C. elegans worms cycle between roaming and dwelling states. Serotonin signaling promotes dwelling, whereas PDF signaling promotes roaming. (B) Schematic circuit diagram shows that some neurons (orange) are directly inhibited by serotonin, whereas other neurons (yellow) are directly activated by PDF. The two signals converge on some neurons (red) to exert opposing effects. Cell  , DOI: ( /j.cell ) Copyright © 2013 Elsevier Inc. Terms and Conditions

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