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Cold Tolerance Encoded in One SNP

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1 Cold Tolerance Encoded in One SNP
Prabha Manishankar, Jörg Kudla  Cell  Volume 160, Issue 6, Pages (March 2015) DOI: /j.cell Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Model of COLD1 Function in Rice Cold Tolerance
The two alleles of the membrane protein COLD1 from the cold-sensitive indica and the more cold-tolerant japonica cultivars of rice differ in one amino acid of the third membrane-spanning domain (japLys187 versus indMet187/Thr187). This difference coincides with elevated cytoplasmic Ca2+ concentration in japonica compared to indica. Cold stress accelerates the GTPase activity of the G-protein α subunit 1 (RGA1) upon RGA1 interaction with COLD1jap, but not with COLD1ind, further increasing cytoplasmic Ca2+ concentration in japonica. Details of the ion conductivity of COLD1 and the identity of the Ca2+ channel(s) involved remain to be established. Cell  , DOI: ( /j.cell ) Copyright © 2015 Elsevier Inc. Terms and Conditions

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