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Small Molecules Take a Big Step by Converting Fibroblasts into Neurons

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1 Small Molecules Take a Big Step by Converting Fibroblasts into Neurons
Kimberley Babos, Justin K. Ichida  Cell Stem Cell  Volume 17, Issue 2, Pages (August 2015) DOI: /j.stem Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Summary of the Chemical Conversion of Fibroblasts into Neurons Two different small-molecule cocktails convert fibroblasts into vGlut1+ or GABA+ neurons, neither one transiting cells through a neural progenitor state. Certain chemicals destabilize the fibroblast state while others seem to induce neurogenesis. (Image credit: Kristen Chen.) Cell Stem Cell  , DOI: ( /j.stem ) Copyright © 2015 Elsevier Inc. Terms and Conditions

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