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Probiotics in Transition

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Presentation on theme: "Probiotics in Transition"— Presentation transcript:

1 Probiotics in Transition
Fergus Shanahan, Timothy G. Dinan, Paul Ross, Colin Hill  Clinical Gastroenterology and Hepatology  Volume 10, Issue 11, Pages (November 2012) DOI: /j.cgh Copyright © 2012 AGA Institute Terms and Conditions

2 Figure 1 Probiotic rationale in settings of low microbial diversity. Low microbial diversity favors ingress of pathogens and limits the protective signaling from the microbiota to the host; host-microbe mismatch may also arise with bacterial overload such as might occur in undeveloped countries. (modified with permission from Shanahan6) Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2012 AGA Institute Terms and Conditions

3 Figure 2 Probiotic strategy when mimicking a specific beneficial effect of the commensal microbiota is desired. (modified with permission from Shanahan6) Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh ) Copyright © 2012 AGA Institute Terms and Conditions


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