1. Insulin content of isolated pancreas and islet morphology.
Insulin content of isolated pancreas and islet morphology. The insulin content of isolated pancreas was measured 3 weeks after the end of treatment (day 37) in multiple low-dose streptozotocin-induced diabetic mice (MLDS mice) (A). Pancreatic islets of the isolated pancreases were stained with H&E on day 37 in MLDS mice (B). (a) Control (Dulbecco's modified Eagle's medium, DMEM); (b) conditioned medium from human exfoliated deciduous teeth (SHED-CM); (c) exendin-4 (Ex-4); and (d) bone marrow-derived mesenchymal stem cells (BM-CM). The data are presented as a mean±SEM value. Scale bars, 100 μm.*p<0.05 versus control; †p<0.05 versus Ex-4; §p<0.05 versus BM-CM.
Takako Izumoto-Akita et al. BMJ Open Diab Res Care 2015;3:e000128
©2015 by American Diabetes Association