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Nat. Rev. Rheumatol. doi: /nrrheum

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1 Nat. Rev. Rheumatol. doi:10.1038/nrrheum.2015.151
Figure 2 The relationship between IgG antibodies and double-stranded DNA Figure 2 | The relationship between IgG antibodies and double-stranded DNA. Binding of IgG antibodies to DNA can occur by monogamous bivalency, wherein both Fab sites of an IgG molecule make contact with a single stretch of DNA. The distance of 136 Å is equivalent to 40 bp in B-form DNA. Permission obtained from the American Society for Clinical Investigation © Papalian, M. et al. Reaction of systemic lupus erythematosus antinative DNA antibodies with native DNA fragments from 20 to 1,200 base pairs. J. Clin. Invest. 65, 469–477 (1980). Permission obtained from the American Society for Clinical Investigation © Papalian, M. et al. Reaction of systemic lupus erythe­matosus antinative DNA antibodies with native DNA fragments from 20 to 1,200 base pairs. J. Clin. Invest. 65, 469–477 (1980) Pisetsky, D. S. (2015) Anti-DNA antibodies — quintessential biomarkers of SLE Nat. Rev. Rheumatol. doi: /nrrheum

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Figure 2 Electromechanical properties of OIHPs

Figure 2 Electromechanical properties of OIHPs
Figure 6 Selected examples of TERS applications in material systems

Figure 6 Selected examples of TERS applications in material systems
Copyright © 2004 American Medical Association. All rights reserved.

Copyright © 2004 American Medical Association. All rights reserved.
Figure 3 The induction of anti-DNA antibodies by bacterial DNA

Figure 3 The induction of anti-DNA antibodies by bacterial DNA
Figure 3 Connexins in cartilage

Figure 3 Connexins in cartilage
Figure 5 Involvement of B cells in SLE

Figure 5 Involvement of B cells in SLE
Figure 1 Historical evolution of the clinical classification and

Figure 1 Historical evolution of the clinical classification and
Figure 2 A timeline summarizing the development of diagnostic tools in rheumatology Figure 2 | A timeline summarizing the development of diagnostic tools.

Figure 2 A timeline summarizing the development of diagnostic tools in rheumatology Figure 2 | A timeline summarizing the development of diagnostic tools.
Figure 2 Representative MSI data obtained from human joints

Figure 2 Representative MSI data obtained from human joints
Figure 1 Rheumatoid arthritis development over time in relation to the level of inflammation Figure 1 | Rheumatoid arthritis development over time in relation.

Figure 1 Rheumatoid arthritis development over time in relation to the level of inflammation Figure 1 | Rheumatoid arthritis development over time in relation.
Nat. Rev. Rheumatol. doi: /nrrheum

Nat. Rev. Rheumatol. doi: /nrrheum
Nat. Rev. Rheumatol. doi: /nrrheum

Nat. Rev. Rheumatol. doi: /nrrheum
Figure 1 Structure of TNF antagonists

Figure 1 Structure of TNF antagonists
Figure 2 Risk factors for sarcopenia

Figure 2 Risk factors for sarcopenia
Figure 2 Assays for detecting antidrug antibodies to TNF inhibitors

Figure 2 Assays for detecting antidrug antibodies to TNF inhibitors
Nat. Rev. Neurol. doi: /nrneurol

Nat. Rev. Neurol. doi: /nrneurol
Subjects gain SLE classification through Systemic Lupus International Collaborating Clinics (SLICC) criteria of low complement, immunological manifestations.

Subjects gain SLE classification through Systemic Lupus International Collaborating Clinics (SLICC) criteria of low complement, immunological manifestations.
Figure 2 Heat map of targeted therapies in autoimmune diseases

Figure 2 Heat map of targeted therapies in autoimmune diseases
Figure 2 Expression of complement activation products in renal samples

Figure 2 Expression of complement activation products in renal samples
Figure 4 Antinuclear antibodies and disease activity in SLE

Figure 4 Antinuclear antibodies and disease activity in SLE

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