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A: OAZ1 mRNA transcript of 775-1, and parental cell lines showing the stop codon introduced by the nonsense mutations in the and transcripts,

Published byBeatrice Atkinson Modified over 6 years ago

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Presentation on theme: "A: OAZ1 mRNA transcript of 775-1, and parental cell lines showing the stop codon introduced by the nonsense mutations in the and transcripts,"— Presentation transcript:

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2 a: OAZ1 mRNA transcript of 775-1, and parental cell lines showing the stop codon introduced by the nonsense mutations in the and transcripts, and the actual stop codon in the parental cell line highlighted in blue. The translation starts codon and the +1-frame shift site are shown in red and green respectively. b: Amino acid sequence of the 775-1, and parental antizyme 1 protein showing the predicted truncations in the (103 amino acids) and775-3 (128 amino acids) sequences, caused by the nonsense mutations, and the full length 228 amino-acid protein sequence.

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