1. Neuroendocrine recovery initiated by cognitive behavioral therapy in women with functional hypothalamic amenorrhea: a randomized, controlled trial 
Vasiliki Michopoulos, Ph.D., Fulvia Mancini, M.D., Tammy L. Loucks, M.P.H., D.P.H., Sarah L. Berga, M.D. 
Fertility and Sterility 
Volume 99, Issue 7, Pages e1 (June 2013)
DOI: /j.fertnstert
Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
Circulatory cortisol with cognitive behavioral therapy in an individual. (A) Circulatory concentrations of cortisol in 15-minute intervals over 24 hours in a woman with FHA before (pre) and after (post) CBT. Meals are indicated by arrows. (B) Circulatory concentrations of cortisol displayed as 8-hour mean in the same woman before (pre) and after (post) CBT.
Fertility and Sterility  , e1DOI: ( /j.fertnstert )
Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

3. Figure 2
Cortisol levels with cognitive behavioral therapy (CBT) versus observation. Mean ± standard error of the mean levels of nocturnal (2400–0745 hours) cortisol levels by treatment arm (observation vs. CBT) and before (pre) and after (post) treatment. The CBT reduced cortisol levels (P=.006). ∗P<.01.
Fertility and Sterility  , e1DOI: ( /j.fertnstert )
Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions

4. Figure 3
Mean ± standard error of the mean of (A) BMI, (B) leptin (∗P=.09), (C) TSH (∗∗P<.01), and (D) free T3 in women who underwent observation or cognitive behavioral therapy (CBT) before (pre) and after (post) treatment. The CBT increased leptin levels (B: P=.09) and increased TSH levels (C: P=.009).
Fertility and Sterility  , e1DOI: ( /j.fertnstert )
Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions