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Serum vs FNA:.

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Presentation on theme: "Serum vs FNA:."— Presentation transcript:

1 Serum vs FNA:

2 Activity Goals

3 Liquid Biopsy in Lung Cancer

4 Applications of Liquid Biopsy

5 Meta-Analysis of Blood vs Tissue Biopsy for EGFR Mutations

6 Genotyping Methodologies ctDNA and cfDNA

7 Questions Clinicians Should Be Asking About Liquid Biopsy Assays

8 Case Study Discussion

9 Guidelines for Biomarker Testing

10 Case Discussion (cont)

11 EGFR Resistance and T790M

12 AURA: Osimertinib (AZD9291) in Treatment-Naïve EGFR-Mutated NSCLC

13 Plasma Testing for T790M Has Good Sensitivity and Likely Good Specificity

14 TIGER-X: Phase 1/2 Study of Rociletinib in Advanced NSCLC

15 Concordance of Plasma and Tissue Biopsy

16 Conclusions and Clinical Pearls

17

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