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Serum vs FNA:
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Activity Goals
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Liquid Biopsy in Lung Cancer
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Applications of Liquid Biopsy
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Meta-Analysis of Blood vs Tissue Biopsy for EGFR Mutations
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Genotyping Methodologies ctDNA and cfDNA
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Questions Clinicians Should Be Asking About Liquid Biopsy Assays
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Case Study Discussion
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Guidelines for Biomarker Testing
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Case Discussion (cont)
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EGFR Resistance and T790M
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AURA: Osimertinib (AZD9291) in Treatment-Naïve EGFR-Mutated NSCLC
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Plasma Testing for T790M Has Good Sensitivity and Likely Good Specificity
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TIGER-X: Phase 1/2 Study of Rociletinib in Advanced NSCLC
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Concordance of Plasma and Tissue Biopsy
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Conclusions and Clinical Pearls
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