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Vitamins U4 AOS 2
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What are vitamins? Organic molecules needed
for the body to function properly to prevent specific diseases Vitamins do not have a common structure are either fat soluble or water soluble Are ‘essential’ except for biotin and vitamin D
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History 1795, British Navy ships carried a mandatory supply of limes or lime juice to prevent scurvy among the sailors – they were given the name “limeys” Japanese Navy gave sailors whole grain barley to ward off beriberi It wasn’t until 1912 that people knew why these “prescriptions” worked to prevent diseases
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Vital-amine Casimir Funk named vitamins – vital amines because they were compounds that contained nitrogen (amines contain nitrogen) and were vital for health Along with Frederick Hopkins, they came up with the idea that scurvy and beriberi were diseases that resulted from the deficiency of certain compounds that could be found in foods.
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Important Vitamins There are 18 vitamins and minerals essential in a healthy diet. Fat soluble vitamins Vitamin A (retinol) Vitamin D (Calciferol) Vitamin E (Tocopherol) Vitamin K (phylloquinone) Water soluble vitamins Vitamin B1(Thiamine) Folic acid Vitamin C (Ascorbic Acid)
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Vitamin Classification
Fat-soluble vs Water soluble Too much of a water soluble vitamin = ok, comes out in urine Too much of a fat soluble vitamin = sickness because it doesn’t dissolve in your urine readily and gets stored in your body. Fat soluble vitamins: All Dogs Eat Kibbles
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Solubility of Vitamins
Solubility depends on the ability of molecules to form hydrogen bonds with water. The more functional groups that hydrogen bond to water, the more soluble the vitamin is in water.
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Fat soluble vitamins
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Water soluble vitamins
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Vitamin A Required for the production of rhodopsin (light-sentistive material in the rods of the retina). Too Little: Nightblindness Xeropthalmia –have difficulty producing tears Effects about 500,000 children in underdeveloped nations Dry mucous membranes Too Much: Makes you think you have a brain tumor Headache, vomiting, nausea, abnormal vision, loss of hair Some precursers can make you turn orange =)
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Vitamin A Poisoning A case of extreme vitamin A poisoning was reported by Artic explorers who killed and ate a polar bear. Those who ate the liver became very ill and three of them lost patches of skin. Later, scientists discovered that 125 g of the liver contains 2.5 yrs worth of Vitamin A for humans.
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How do we get vitamin A? 2 Chemicals: Retinoids and carotenoids
Retinoids – body can use right away Carotenoids – body can change it into a retinoid Beta-carotene (Why are carrots good for your eyes? Have you ever seen a rabbit with glasses?) Carotenoids don’t get stored in liver Foods with Vitamin A Cereal, oatmeal Fruit: apricots, canteloupe, mango Veggies: carrots, kale, peas, sweet peppers Meat: Liver Milk
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Vitamin C Required for Too Little: Too Much:
Production of collagen: the protein of connective tissue. Antioxidant Protects immune system, helps fight off infection, reduces allergic reactions Too Little: Scurvy (bleeding gums; tooth loss; nosebleeds; bruising; painful or swollen joints; shortness of breath, increased susceptibility to infection, skin rashes; muscle pains, slow wound healing) Too Much: More than 1000 mg may cause upset stomach, diarrhea, or constipation
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How do we get Vitamin C? On the label, look for: Foods with Vit C
Did you know that many foods are preserved with sodium nitrite to prevent the growth of bacteria. At high T, nitrite + protein forms carcinogen. Vitamin C prevents that reaction so it is added to processed meat, too. On the label, look for: Sodium ascorbate Isoacrobate Ascorbic acid Foods with Vit C Cereal Meat: Liver Fruit: Canteloupe, grapefruit, mango, orange, strawberries, Vegetables: Asparagus, broccoli, brussel sprouts, kale, kohlrabi, sweet peppers, snow peas (cooked) sweet potato
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Vitamin D Required for the uptake of calcium and phosphorus from food.
Too little: can cause weak bones (Rickets) in children In adults: osteomalacia (soft bones, fracture easily) Too much: Kidney stones and hard lumps of calcium in muscles and organs Headache, nausea, vomiting, high blood pressure, retarded physical growth and mental retardation in children, fetal abnormalities
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How do we get Vitamin D? 3 forms Foods with 25% of RDA
Calciferol: occurs in fish oils, egg yolks Cholecaliferol: created when sunlight hits skin, reacting with steroids in body fat just underneath skin Ergocalciferol: found in plants Foods with 25% of RDA Salmon or tuna Eggs Milk Some people claim that you should not use sunscreen so that your body can use the sunlight to produce Vitamin D. Most doctors, though, advise getting Vitamin D through your food and wear a high SPF sunscreen at all times.
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Cooking and vitamin absorption
Studies show that cooking foods can cause a decrease in the amount of vitamins in the food Water soluble vitamins dissolve in cooking water Some vitamins are broken down by heating Some vitamins, though, are better than no vitamins. So eat your vegetables, cooked or not.
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Comparison of water soluble and fat soluble vitamins
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