1. Clinical Scenario: Encouraging Adherence in Patients with Schizophrenia

2. Introduction

3. Clinical Case: Emma

4. Clinical Case: Emma (cont)

5. Clinical Case: Main Points

6. Progressive Stages of Illness in Schizophrenia

7. Time to Remission From Start of Treatment in First-Episode Schizophrenia

8. Clinical Features of Schizophrenia and Functional Decline

9. Deterioration in Functioning, Relapse, and Adherence

10. Risk of Symptom Recurrence Declines With Maintenance Treatment: Systematic Review

11. Stratifying Schizophrenia Based on Long-Term Outcome

12. Schizophrenia: Possible Subtypes

13. Emma: Clinical Signs of Early Deterioration?

14. Reasons for Poor Medication Adherence in Schizophrenia

15. Reasons for Treatment Discontinuation: Poor Response or Symptom Worsening Adherence in Schizophrenia

16. Schizophrenia as a Chronic Illness: Social Outcome

17. Emma: How to Avoid Another Relapse?

18. Adherence to Treatment Among Outpatients With Schizophrenia

19. Social and Other Consequences of Relapse

20. First 5 Reasons Psychiatrists Give for Deciding Against LAIs in First-Episode Schizophrenia

21. LAIs Reduce Risk for Hospitalization Compared With Oral Antipsychotics in Mirror-Image Studies

22. Treating Subsets of Patients Who Have Schizophrenia

23. Concluding Remarks: Emma

24. Abbreviations