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Volume 53, Issue 6, Pages 1129-1137 (June 2008)
Progress in Understanding Androgen-Independent Prostate Cancer (AIPC): A Review of Potential Endocrine-Mediated Mechanisms Fritz H. Schröder European Urology Volume 53, Issue 6, Pages (June 2008) DOI: /j.eururo Copyright © 2008 European Association of Urology Terms and Conditions
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Fig. 1 AR expression in BPH and endocrine therapy-unresponsive prostate cancer. Samples obtained via transurethral resection. AR=androgen receptor; BPH=benign prostatic hyperplasia. Reprinted with permission from van der Kwast TH et al. Int J Cancer 1991;48:189–93. European Urology , DOI: ( /j.eururo ) Copyright © 2008 European Association of Urology Terms and Conditions
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Fig. 2 Substrate cholesterol. Tissue levels in normal prostate, benign prostatic hyperplasia (BPH), prostatic carcinoma (Ca), and fibromuscular stroma (FM). Reprinted with permission from Goldstein. Ph.D. dissertation, Rutgers University, New Brunswick, NJ, 1975. European Urology , DOI: ( /j.eururo ) Copyright © 2008 European Association of Urology Terms and Conditions
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Fig. 3 Pathway of androgen synthesis and involved enzymes.
European Urology , DOI: ( /j.eururo ) Copyright © 2008 European Association of Urology Terms and Conditions
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