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Sodium channel blockers in KCNQ2-encephalopathy: Lacosamide as a new treatment option  Susanne Schubert-Bast, Peter Hofstetter, Doris Fischer, Rolf Schloesser,

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Presentation on theme: "Sodium channel blockers in KCNQ2-encephalopathy: Lacosamide as a new treatment option  Susanne Schubert-Bast, Peter Hofstetter, Doris Fischer, Rolf Schloesser,"— Presentation transcript:

1 Sodium channel blockers in KCNQ2-encephalopathy: Lacosamide as a new treatment option 
Susanne Schubert-Bast, Peter Hofstetter, Doris Fischer, Rolf Schloesser, Georgia Ramantani, Matthias Kieslich  Seizure - European Journal of Epilepsy  Volume 51, Pages (October 2017) DOI: /j.seizure Copyright © 2017 British Epilepsy Association Terms and Conditions

2 Fig. 1 EEG recordings: a) first EEG recording: burst suppression pattern at the age of 2 days. b) EEG before treatment with lacosamide at the age of one week: subclinical seizure pattern evolving from left frontal area. c) EEG before treatment with lacosamide at the age of 3 weeks: multifocal epileptic discharges, poor background organization. d) EEG 3 weeks after starting lacosamide treatment at the age of 6 weeks: better background organization, fewer multifocal discharges. Seizure - European Journal of Epilepsy  , DOI: ( /j.seizure ) Copyright © 2017 British Epilepsy Association Terms and Conditions


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