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Better preservation of endothelial function and decreased activation of the fetal renin- angiotensin pathway with the use of pulsatile flow during experimental.

Published byΣτυλιανός Μαρκόπουλος Modified over 5 years ago

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Presentation on theme: "Better preservation of endothelial function and decreased activation of the fetal renin- angiotensin pathway with the use of pulsatile flow during experimental."— Presentation transcript:

1 Better preservation of endothelial function and decreased activation of the fetal renin- angiotensin pathway with the use of pulsatile flow during experimental fetal bypass  Catherine Vedrinne, MDa, François Tronc, MDb, Stéphane Martinot, MVDc, Jacques Robin, MDb, Anne-Marie Allevard, PhDd, Madeleine Vincent, PhDd, Jean Jacques Lehot, MDa, Michel Franck, MVDc, Gérard Champsaur, MDb  The Journal of Thoracic and Cardiovascular Surgery  Volume 120, Issue 4, Pages (October 2000) DOI: /mtc Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

2 Fig. 1 Fetal plasma level of lactate (mmol · L–1): Measurements were made after fetal exteriorization, on bypass, and at the end of bypass. Black circle, Within-group differences, P < .05. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

3 Fig. 2 Mean pump flow evolution (mL · min–1 · kg–1) and between-group comparison. T10, 10 minutes of bypass; T60, 60 minutes of bypass. *Intergroup differences, pulsatile-flow versus steady-flow group; P < .05. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

4 Fig. 3 Mean distal aortic flow evolution (mL · min–1 · kg–1) and between-group comparison. Tb, Baseline time; Tc, cannulation time; T10 to T60, every 10 minutes after initiation of bypass. *Intergroup differences, pulsatile-flow versus steady-flow group; P < .05. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

5 Fig. 4 Mean umbilical flow evolution (mL · min–1 · kg–1) and between-group comparison. Tb, Baseline time; Tc, cannulation time; T10 to T60, every 10 minutes after initiation of bypass. *Intergroup differences, pulsatile-flow versus steady-flow group; P < .05. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

6 Fig. 5 Mean fetal systemic vascular resistances evolution (mm Hg · mL–1 · min–1 · kg–1) and between-group comparison. T10, 10 minutes of bypass; T60, 60 minutes of bypass. *Intergroup differences, pulsatile-flow versus steady-flow group; P < .05. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

7 Fig. 6 Mean placental vascular resistances evolution (mm Hg · mL–1 · min–1 · kg–1) and between-group comparison. Tb, Baseline time; Tc, cannulation time; T10 to T60, every 10 minutes after initiation of bypass. *Intergroup differences, pulsatile-flow versus steady-flow group; P < .05. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /mtc ) Copyright © 2000 American Association for Thoracic Surgery Terms and Conditions

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