Presentation is loading. Please wait.

Presentation is loading. Please wait.

Volume 86, Issue 6, Pages (December 2014)

Similar presentations


Presentation on theme: "Volume 86, Issue 6, Pages (December 2014)"— Presentation transcript:

1 Volume 86, Issue 6, Pages 1130-1139 (December 2014)
A useful scoring system for the prediction and management of delayed graft function following kidney transplantation from cadaveric donors  Marion Chapal, Florent Le Borgne, Christophe Legendre, Henri Kreis, Georges Mourad, Valérie Garrigue, Emmanuel Morelon, Fanny Buron, Lionel Rostaing, Nassim Kamar, Michèle Kessler, Marc Ladrière, Jean-Paul Soulillou, Katy Launay, Pascal Daguin, Lucile Offredo, Magali Giral, Yohann Foucher  Kidney International  Volume 86, Issue 6, Pages (December 2014) DOI: /ki Copyright © 2014 International Society of Nephrology Terms and Conditions

2 Figure 1 Positive and negative predictive values according to the threshold values. These analyses were performed from the training sample (n=1222, 16 observations removed because of missing data). If the score is higher than the threshold, the test is considered positive and the patient is at-risk of delayed graft function (DGF). In contrast, if the score is lower than the threshold, the test is negative and the patient is not considered at-risk of DGF. The percentage of patients with DGF was around 50% if the delayed graft function score (DGFS) was higher than The percentage of patients without DGF was around 88% if the DGFS was lower than −0.50. Kidney International  , DOI: ( /ki ) Copyright © 2014 International Society of Nephrology Terms and Conditions

3 Figure 2 Receiver-operating characteristic (ROC) curves to evaluate the prognostic capacity of the different markers performed from the validation sample. The composite score (red continuous line, n=561, area under ROC curve (AUC)=0.73, 95% confidence interval (CI)=(0.68, 0.77)). The cold ischemia time (black-dashed line, n=561, AUC=0.64, 95% CI=(0.59, 0.69)). The score proposed by Jeldres et al. (blue-dotted line, n=226, AUC=0.64, 95% CI=(0.56, 0.72)). Kidney International  , DOI: ( /ki ) Copyright © 2014 International Society of Nephrology Terms and Conditions

4 Figure 3 Evaluation of the calibration of the model. The observed and predicted delayed graft function (DGF) probabilities were computed according to 10 delayed graft function score (DGFS) intervals. The goodness of the fit cannot be rejected (P=0.1054, Hosmer–Lemeshow statistic). Kidney International  , DOI: ( /ki ) Copyright © 2014 International Society of Nephrology Terms and Conditions


Download ppt "Volume 86, Issue 6, Pages (December 2014)"

Similar presentations


Ads by Google