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Mammalian Target of Rapamycin Inhibitors in Clinical Practice: Case Reports of Everolimus in Renal Cell Carcinoma  Sergio Bracarda, Alain Ravaud, Marino.

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Presentation on theme: "Mammalian Target of Rapamycin Inhibitors in Clinical Practice: Case Reports of Everolimus in Renal Cell Carcinoma  Sergio Bracarda, Alain Ravaud, Marino."— Presentation transcript:

1 Mammalian Target of Rapamycin Inhibitors in Clinical Practice: Case Reports of Everolimus in Renal Cell Carcinoma  Sergio Bracarda, Alain Ravaud, Marino Chiodi  European Urology Supplements  Volume 8, Issue 10, Pages (November 2009) DOI: /j.eursup Copyright © 2009 European Association of Urology Terms and Conditions

2 Fig. 1 (a) Lung computed tomography (CT) scan and (b) abdominal CT scan of a patient with metastatic renal cell carcinoma prior to treatment with everolimus; (c) lung CT scan and (d) abdominal CT scan of patient 16 mo after initiation of everolimus treatment. Arrows indicate metastases. European Urology Supplements 2009 8, DOI: ( /j.eursup ) Copyright © 2009 European Association of Urology Terms and Conditions

3 Fig. 2 (a) Computed tomography scan showing mediastinal lymph node metastases; (b) evidence of significant reduction after 8 mo of treatment with open-label everolimus. European Urology Supplements 2009 8, DOI: ( /j.eursup ) Copyright © 2009 European Association of Urology Terms and Conditions

4 Fig. 3 Summary of responses to treatment over time in two patients with metastatic renal cell carcinoma. Approximate timelines are given. IFN-α=interferon alfa; VEGF=vascular endothelial growth factor. European Urology Supplements 2009 8, DOI: ( /j.eursup ) Copyright © 2009 European Association of Urology Terms and Conditions


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