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Microvascular oxygen consumption during sickle cell pain crisis

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Presentation on theme: "Microvascular oxygen consumption during sickle cell pain crisis"— Presentation transcript:

1 Microvascular oxygen consumption during sickle cell pain crisis
by Carol A. Rowley, Allison K. Ikeda, Miles Seidel, Tiffany C. Anaebere, Matthew D. Antalek, Catherine Seamon, Anna K. Conrey, Laurel Mendelsohn, James Nichols, Alexander M. Gorbach, Gregory J. Kato, and Hans Ackerman Blood Volume 123(20): May 15, 2014 ©2014 by American Society of Hematology

2 Elevated oxygen consumption, neutrophil count, and CRP during sickle cell pain crisis.
Elevated oxygen consumption, neutrophil count, and CRP during sickle cell pain crisis. Thenar eminence microvascular oxygen consumption (A; VO2), absolute (Abs) neutrophil count (B), and CRP levels (C) were greater among sickle cell disease (SCD) patients in pain crisis than among patients in steady-state or healthy individuals. Horizontal lines indicate the median for each group. Significance levels are indicated by *P < .05, **P < .01, and ns (not significant). Carol A. Rowley et al. Blood 2014;123: ©2014 by American Society of Hematology


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